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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

NA Semax 50mg

$210.00

NA Semax 50mg is an N-acetylated analog of the synthetic heptapeptide Semax, developed for laboratory investigation of neurotrophic signaling pathways and peptide-mediated transcriptional regulation in controlled experimental systems.

NA Semax functions in research models as a melanocortin-derived fragment capable of influencing intracellular cascades associated with brain-derived neurotrophic factor (BDNF) expression, cAMP/PKA signaling, and CREB-dependent transcriptional mechanisms.

The N-acetyl modification enhances peptide stability in vitro, supporting structured studies of receptor-mediated signaling dynamics and neurochemical pathway modulation within experimental neurobiology frameworks.

For research use only. Not for human consumption.

References:
Ashmarin IP et al., Neurosci Behav Physiol, 1995;25(2):132–138
Dolotov OV et al., Acta Naturae, 2006;1(2):37–44
Volkova AA et al., Bull Exp Biol Med, 2013;155(2):225–227

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Overview of NA Semax 50mg

NA Semax 50mg is a synthetic neuropeptide analog derived from the ACTH (4–10) fragment sequence and modified through N-acetylation to enhance molecular stability in laboratory research environments. This higher-concentration format provides researchers with increased total peptide content suitable for extended or multi-phase experimental protocols.

NA Semax is structurally based on the heptapeptide sequence Met-Glu-His-Phe-Pro-Gly-Pro and is engineered to support structured investigations of neurotrophic signaling, intracellular transcription factor modulation, and melanocortin pathway research.

Supplied in lyophilized sterile powder form, NA Semax 50mg is intended strictly for laboratory research and analytical applications.


Molecular Characteristics

NA Semax incorporates N-terminal acetylation, a modification that improves peptide resistance to enzymatic degradation in vitro. This structural enhancement supports prolonged stability in controlled research systems.

In laboratory investigations, NA Semax 50mg is commonly studied for:

  • Brain-derived neurotrophic factor (BDNF) pathway modeling

  • cAMP-dependent intracellular signaling analysis

  • CREB activation research

  • Melanocortin receptor pathway studies

  • Neurochemical transcription regulation

  • Peptide-mediated intracellular cascade evaluation

The 50mg format is particularly suitable for research requiring multiple assay cycles or high-volume experimental modeling.


Mechanism of Action (Research Context)

In controlled laboratory environments, NA Semax 50mg is studied for its involvement in intracellular signaling pathways associated with neurotrophic factor expression and melanocortin-derived peptide activity.

Experimental models have examined:

  • Modulation of BDNF gene expression

  • Activation of cAMP/PKA signaling cascades

  • CREB phosphorylation mechanisms

  • Regulation of neuropeptide-associated transcription

  • Peptide-mediated intracellular communication networks

By utilizing the N-acetylated analog, researchers can investigate how enhanced peptide stability influences signaling kinetics and transcriptional modulation within experimental systems.


Research Applications

NA Semax 50mg is frequently referenced in laboratory investigations involving:

  1. Neurotrophic signaling pathway research

  2. BDNF expression modeling

  3. Melanocortin receptor pharmacology

  4. Intracellular second messenger cascade analysis

  5. Peptide-mediated transcription factor research

  6. Neurochemical pathway integration studies

In molecular neuroscience laboratories, NA Semax 50mg provides a scalable research compound for structured evaluation of peptide-driven intracellular signaling.

Researchers studying neuropeptide biology commonly consult peer-reviewed databases such as the National Center for Biotechnology Information (NCBI) for foundational literature on melanocortin and BDNF pathways.


Stability and Laboratory Handling

NA Semax 50mg is supplied as a lyophilized white powder to preserve peptide integrity and minimize hydrolytic degradation before reconstitution.

Laboratory handling recommendations include:

  • Store under recommended refrigerated conditions

  • Avoid repeated freeze–thaw cycles

  • Reconstitute with sterile laboratory-grade solvent

  • Follow institutional peptide handling protocols

Lyophilization ensures consistent molecular stability and reproducibility across structured experimental protocols.


Product Specifications

  • Compound: NA Semax

  • Classification: Synthetic neuropeptide analog

  • Structure: N-acetylated Semax (ACTH fragment derivative)

  • Strength: 50mg

  • Form: Lyophilized sterile powder

  • Appearance: White to off-white solid

  • Storage: Refrigerated conditions recommended

  • Intended Use: Laboratory research only


Analytical Verification

Each batch of NA Semax 50mg undergoes analytical verification to confirm identity and purity. Testing methodologies may include:

  • High-performance liquid chromatography (HPLC)

  • Mass spectrometry analysis

  • Structural sequence validation

  • Batch-to-batch consistency testing

Lot numbers are assigned to ensure traceability and support structured research documentation.


Broader Scientific Context

NA Semax 50mg is widely referenced in laboratory research exploring neurotrophic signaling networks, melanocortin-derived peptide mechanisms, and intracellular transcriptional regulation. The higher-dose format allows for expanded research design flexibility in multi-phase experimental frameworks.

This peptide contributes to ongoing investigation into structure-function relationships within neurochemical signaling systems.


Compliance Notice

NA Semax 50mg is intended strictly for laboratory research use.

This product is not approved for human consumption, therapeutic application, or clinical use. It is sold exclusively for in vitro research, analytical testing, and scientific investigation by qualified professionals.

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