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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

ARA-290 16mg

Rated 4.78 out of 5 based on 9 customer ratings

$65.00

ARA-290 is a synthetic research peptide engineered from the B-helix domain of erythropoietin. It selectively binds the EPOR–CD131 receptor complex, activating the innate repair receptor (IRR) pathway without stimulating erythropoiesis. Preclinical models show ARA-290 modulates cytokine activity, endothelial integrity, and neuroimmune signaling, making it a tool for studies on inflammation and tissue protection.

For research use only. Not for human consumption.

References:
Brines M et al., Proc Natl Acad Sci USA, 2008 105(31):10925–10930
Ehrenreich H et al., Mol Med, 2010 16(9-10): 440–446
Ostrowski D et al PLoS One, 2017 12(10): e0185838

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ARA-290 16mg is a synthetic peptide derived from the tertiary structure of erythropoietin (EPO) and studied in controlled laboratory environments for its interaction with tissue-protective receptor signaling pathways. In experimental biological systems, ARA-290 16mg is examined for its selective engagement with innate repair receptor complexes and downstream intracellular signaling cascades.

This peptide is structurally designed to mimic specific regions of erythropoietin responsible for tissue-protective signaling while excluding erythropoietic activity in research models. Laboratory investigations involving ARA-290 16mg focus on receptor specificity, molecular signaling responses, and peptide-mediated regulatory mechanisms under controlled experimental conditions.

Research Overview

ARA-290 16mg has been studied in preclinical models exploring tissue-protective signaling pathways and cytokine-mediated regulatory responses. Scientific interest in this compound centers on its ability to selectively interact with heteromeric receptor complexes associated with cellular repair signaling in laboratory systems.

Experimental research evaluates how ARA-290 16mg engages innate repair receptor pathways distinct from classical erythropoietin receptors. Investigators frequently assess intracellular signaling markers, phosphorylation events, and transcriptional responses following receptor activation in defined biological environments.

In controlled research settings, ARA-290 16mg serves as a reference compound for studying peptide-based modulation of inflammatory signaling pathways and cellular stress response mechanisms. These investigations are conducted strictly for laboratory research purposes.

Mechanism of Study

The mechanism of study for ARA-290 16mg involves analysis of receptor-mediated activation of tissue-protective signaling cascades. Research models examine how the peptide interacts with the innate repair receptor complex, which differs structurally and functionally from traditional erythropoietin receptor pathways.

Upon receptor engagement in laboratory environments, downstream signaling cascades such as JAK/STAT and other intracellular regulatory pathways may be evaluated. Investigators monitor molecular markers associated with cytokine signaling modulation, transcription factor activation, and cellular stress response dynamics.

Studies emphasize receptor selectivity, structural integrity, and reproducibility across experimental models. Analytical frameworks focus on peptide stability, binding affinity, and downstream molecular responses in controlled research systems.

Applications in Research

ARA-290 16mg is commonly utilized in laboratory models investigating cytokine signaling regulation and tissue-protective pathway activation. Researchers may analyze intracellular communication networks and stress-response markers when studying this peptide under experimental conditions.

Preclinical research frequently examines molecular interactions associated with inflammatory signaling modulation and regulatory pathway activation. These studies contribute to broader scientific understanding of receptor-specific peptide signaling frameworks.

Product Specifications

• 16mg per vial
• Lyophilized powder for enhanced stability
• ≥99% HPLC verified purity
• Third-party tested
• Research use only
• Store at -20°C

ARA-290 16mg is supplied as a lyophilized powder to preserve molecular structure and stability during storage and transit. Proper laboratory handling procedures are recommended to maintain analytical consistency prior to experimental preparation.

Certificate of Analysis

Each batch of ARA-290 16mg undergoes independent analytical verification to confirm purity and molecular identity. High-Performance Liquid Chromatography (HPLC) testing confirms ≥99% purity prior to release for research distribution.

Additional analytical characterization methods may include mass spectrometry and structural validation procedures to ensure molecular consistency across batches. Certificates of Analysis may be available upon request for laboratory documentation purposes.

Laboratory Handling & Storage

ARA-290 16mg should be stored in a controlled laboratory environment at -20°C prior to reconstitution. Lyophilized peptide compounds are designed to maintain stability when handled according to validated laboratory standards.

Upon preparation for experimental applications, researchers typically follow established laboratory protocols to preserve structural integrity and ensure reliable analytical outcomes.

Analytical Characterization

ARA-290 16mg is characterized using chromatographic and molecular analytical techniques designed to verify peptide sequence integrity and purity levels. HPLC testing confirms purity specifications prior to research distribution.

Research laboratories may employ additional techniques such as mass spectrometry and peptide mapping to validate molecular weight accuracy and structural consistency.

Frequently Asked Questions

Q: Is ARA-290 16mg intended for human consumption?
A: No. This compound is strictly intended for laboratory research use only.

Q: What receptor pathway is studied with ARA-290 16mg?
A: ARA-290 16mg is studied for its interaction with innate repair receptor complexes in experimental models.

Q: How is purity verified?
A: Purity is confirmed through validated High-Performance Liquid Chromatography (HPLC) testing methods.

For research use only. Not for human consumption.

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