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Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10)

$725.00

GHRP-2 and CJC-1295 no DAC (Mod GRF 1-29) are synthetic research peptides used together in experimental models to investigate growth hormone axis regulation and somatotropic signaling pathways. GHRP-2 is a potent hexapeptide growth hormone secretagogue that activates the growth hormone secretagogue receptor (GHS-R1a), triggering Gq/PLC-dependent calcium signaling involved in GH release and hypothalamic–pituitary feedback regulation. CJC-1295 no DAC is a stabilized analog of growth hormone–releasing hormone (GHRH 1-29) that selectively activates the GHRH receptor, stimulating adenylate cyclase and cAMP-mediated signaling in pituitary somatotrophs. Preclinical research employs the combined activation of GHS-R1a and GHRH receptors to examine synergistic GH secretion, receptor pharmacology, and endocrine signaling dynamics in controlled laboratory settings.

For research use only. Not for human consumption.

References:
Bowers CY et al., Ann NY Acad Sci, 1998 865:244–249
Frohman LA et al., Endocr Rev, 2001 22(6):606–648
Jacks T et al., Endocrinology, 1994 134(2):744–750

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Research Overview

GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) is a structured dual-pathway research peptide stack designed for laboratory investigation of growth hormone regulatory signaling. This combination allows researchers to study simultaneous activation of the growth hormone secretagogue receptor (GHS-R1a) and the growth hormone–releasing hormone (GHRH) receptor under controlled in vitro conditions.

GHRP-2 is a synthetic hexapeptide classified as a growth hormone releasing peptide (GHRP) that interacts with the ghrelin receptor (GHS-R1a). CJC-1295 no DAC, also known as Mod GRF 1-29, is a synthetic analog of growth hormone–releasing hormone designed for selective activation of the GHRH receptor.

When studied together in laboratory systems, GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) enables researchers to evaluate dual receptor activation models and analyze potential intracellular signaling interactions between these two endocrine pathways.

This product is supplied as lyophilized sterile powder in multi-vial format for structured laboratory research applications.


Molecular Characteristics

GHRP-2

GHRP-2 is a synthetic hexapeptide engineered to activate the GHS-R1a receptor. In laboratory research, GHRP-2 is studied for:

  • Ghrelin receptor activation

  • Intracellular calcium mobilization

  • Phospholipase C (PLC) pathway activation

  • Hypothalamic–pituitary axis modeling

  • Endocrine signaling cascade analysis

CJC-1295 no DAC (Mod GRF 1-29)

CJC-1295 no DAC is a modified growth hormone–releasing hormone analog that binds selectively to the GHRH receptor. Unlike DAC-bound versions, the no DAC form is shorter-acting in laboratory models, allowing researchers to evaluate pulsatile receptor activation in experimental systems.

CJC-1295 no DAC is studied for:

  • GHRH receptor activation

  • cAMP pathway modulation

  • Adenylate cyclase activation

  • Transcription factor regulation

  • Growth hormone signaling pathway modeling


Mechanism of Action (Research Context)

In controlled laboratory environments, GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) allows researchers to evaluate dual-pathway activation:

GHRP-2 Pathway

  • Binds to GHS-R1a receptor

  • Activates phospholipase C

  • Promotes IP3 production

  • Mobilizes intracellular calcium

  • Engages protein kinase C signaling

CJC-1295 no DAC Pathway

  • Binds to GHRH receptor

  • Activates adenylate cyclase

  • Increases cyclic AMP (cAMP)

  • Stimulates protein kinase A (PKA) signaling

  • Modulates transcriptional regulation

When studied in combination, researchers can analyze:

  • Receptor cross-talk

  • Signal amplification models

  • Synergistic intracellular cascade activation

  • Comparative receptor desensitization dynamics

This dual-pathway framework is commonly referenced in structured endocrine signaling research.


Research Applications

GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) is frequently used in laboratory studies involving:

  1. Dual receptor activation modeling

  2. Hypothalamic–pituitary axis research

  3. Ghrelin and GHRH pathway interaction studies

  4. Intracellular second messenger analysis

  5. Comparative endocrine signaling evaluation

  6. Receptor cross-talk investigations

In molecular biology laboratories, this research stack provides a framework for analyzing how two independent receptor systems interact within a shared endocrine regulatory network.

Researchers exploring endocrine signaling mechanisms often reference peer-reviewed scientific databases such as the National Center for Biotechnology Information (NCBI) for foundational literature on GHS and GHRH receptor biology.


Stability and Laboratory Handling

Both peptides in GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) are supplied in lyophilized form to preserve structural stability and minimize degradation prior to reconstitution.

For laboratory use:

  • Store under recommended refrigerated conditions

  • Avoid repeated freeze–thaw cycles

  • Reconstitute using sterile laboratory-grade solvent

  • Follow institutional peptide handling protocols

Lyophilization ensures consistent molecular integrity and supports reproducibility across structured research applications.


Product Specifications

GHRP-2

  • Classification: Growth Hormone Releasing Peptide

  • Strength: 5mg per vial

  • Quantity: 10 vials

  • Structure: Synthetic hexapeptide

CJC-1295 no DAC (Mod GRF 1-29)

  • Classification: GHRH Analog

  • Strength: 5mg per vial

  • Quantity: 10 vials

  • Structure: Modified 29-amino acid peptide

  • Form: Lyophilized sterile powder

  • Appearance: White to off-white solid

  • Intended Use: Laboratory research only


Analytical Verification and Quality Standards

Each batch of GHRP-2 and CJC-1295 no DAC undergoes analytical verification to confirm peptide identity and purity. Testing procedures may include:

  • High-performance liquid chromatography (HPLC)

  • Mass spectrometry analysis

  • Structural integrity verification

  • Batch-to-batch consistency validation

Lot numbers are assigned to support traceability and research documentation.


Broader Scientific Context

GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) is widely referenced in laboratory research exploring endocrine signaling networks and receptor-mediated intracellular cascade modulation. The coordinated activation of GHS-R1a and GHRH receptors provides researchers with a structured model for analyzing complex hormonal signaling interactions in controlled experimental systems.


Compliance Notice

GHRP-2 (5mg x 10), CJC-1295 no DAC (5mg x 10) is intended strictly for laboratory research use.

This product is not approved for human consumption, therapeutic application, or clinical use. It is sold exclusively for in vitro research, analytical testing, and scientific investigation by qualified professionals.

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