KPV (Ac-KPV-NH2) 30mg

Overview of KPV (Ac-KPV-NH2) 30mg

KPV (Ac-KPV-NH2) 30mg is a synthetic tripeptide fragment corresponding to the Lys-Pro-Val sequence derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH). In laboratory research, KPV is studied for its involvement in inflammatory signaling pathways, immune response modulation, and transcription factor regulation.

The acetylated and amidated structure (Ac-KPV-NH2) improves peptide stability in experimental systems by enhancing resistance to enzymatic degradation and increasing structural integrity in vitro.

Supplied in lyophilized form, KPV (Ac-KPV-NH2) 30mg is intended strictly for laboratory research and analytical applications.

Molecular Characteristics

KPV is a tripeptide consisting of:

• Lysine (K)

• Proline (P)

• Valine (V)

The acetyl (Ac) modification at the N-terminus and amide (NH2) modification at the C-terminus provide enhanced stability for research use.

In laboratory environments, KPV (Ac-KPV-NH2) 30mg is commonly studied for:

• NF-κB pathway modulation

• Cytokine signaling cascade analysis

• Transcriptional regulation research

• Immune cell signaling models

• Epithelial barrier pathway investigations

Its small size allows for focused studies on peptide-mediated intracellular signaling mechanisms.

Mechanism of Action (Research Context)

In controlled in vitro research systems, KPV (Ac-KPV-NH2) 30mg is investigated for its influence on inflammatory signaling pathways, particularly those involving NF-κB transcriptional activation.

Experimental models have examined:

• Modulation of NF-κB nuclear translocation

• Downregulation of pro-inflammatory cytokine expression

• Intracellular signaling cascade adjustment

• Epithelial cell inflammatory response modeling

• Peptide-mediated transcription factor interaction

Because KPV is derived from α-MSH, it is frequently studied within broader melanocortin signaling research frameworks.

Researchers utilize KPV (Ac-KPV-NH2) 30mg to explore peptide fragment activity independent of full-length hormone systems.

Research Applications

KPV (Ac-KPV-NH2) 30mg is frequently referenced in laboratory investigations involving:

1. Cytokine signaling pathway research

2. NF-κB transcription regulation studies

3. Immune response modeling

4. Peptide-mediated anti-inflammatory pathway analysis

5. Epithelial barrier signaling research

6. Comparative melanocortin fragment studies

In molecular biology laboratories, KPV provides a simplified peptide model for evaluating transcriptional and inflammatory signaling interactions.

Researchers exploring melanocortin and immune signaling mechanisms often reference peer-reviewed databases such as the National Center for Biotechnology Information (NCBI) for foundational literature.

Structural Stability and Handling

KPV (Ac-KPV-NH2) 30mg is supplied as a lyophilized sterile powder to preserve peptide integrity and reduce hydrolytic degradation.

Laboratory handling recommendations:

• Store under recommended refrigerated conditions

• Avoid repeated freeze–thaw cycles

• Reconstitute with sterile laboratory-grade solvent

• Follow institutional peptide handling protocols

Lyophilization ensures consistent molecular stability across structured research applications.

Product Specifications

• Compound: KPV (Ac-KPV-NH2)

• Classification: Synthetic tripeptide fragment

• Sequence: Lys-Pro-Val (Acetylated / Amidated)

• Strength: 30mg

• Form: Lyophilized sterile powder

• Appearance: White to off-white solid

• Storage: Refrigerated conditions recommended

• Intended Use: Laboratory research only

Analytical Verification

Each batch of KPV (Ac-KPV-NH2) 30mg undergoes analytical verification to confirm identity and purity, including:

• High-performance liquid chromatography (HPLC)

• Mass spectrometry analysis

• Sequence validation

• Batch consistency testing

Lot numbers are assigned for traceability within structured research documentation systems.

Broader Scientific Context

KPV (Ac-KPV-NH2) 30mg is widely referenced in laboratory research exploring inflammatory signaling and melanocortin peptide fragment biology. By isolating a minimal functional sequence from α-MSH, researchers can investigate peptide-specific modulation of intracellular pathways without systemic endocrine variables.

This focused approach contributes to deeper understanding of peptide structure-function relationships within immune signaling research.

Compliance Notice

KPV (Ac-KPV-NH2) 30mg is intended strictly for laboratory research use.

This product is not approved for human consumption, therapeutic application, or clinical use. It is sold exclusively for in vitro research, analytical testing, and scientific investigation by qualified professionals.